Chromosomal Location of MN Blood Group Locus

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Comparison of human MM, NN, and MN blood group antigens.

Types MM, NN, and MN blood group substances have been isolated. All three materials are glycoproteins containing about 24 % iV-acetyhreuraminic acid, 10 % galactosamine, 5% glucosamine, and 14% galactose. The hexosamines appear to be N-acetylated. Amino acid analysis of the glycoproteins reveals them to be similar in composition and to be especially rich in serine and threonine. Treatment of th...

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Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus.

Many tumors are characterized by recurrent translocations between a tissue-specific gene and a proto-oncogene. The juxtaposition of the Ig heavy chain gene and Myc in Burkitt's lymphoma and in murine plasmacytoma is a classic example. Regulatory elements within the heavy chain constant region locus are required for Myc translocation and/or deregulation. However, many genes are regulated by cis-...

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MN blood group activity of the blood components other than the red cells.

SAGISAKA, K. and TOKIWA, K . MN Blood Group Activity of the Blood Components Other Than the Red Cells. Tohoku J. exp. Med., 1973, 109 (1), 1-6 The presence of M and N antigens in the blood components other than the red cells and various tissues has not been settled yet . The elution method in combination with antiglobulin test reported by the present authors has been used for grouping the stain...

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ژورنال

عنوان ژورنال: Science

سال: 1969

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.164.3884.1187